General Information about Cialis®
Cialis ®
What is Cialis (tadalafil)?
Cialis is in a class of medications known as PDE-5 inhibitors, which are used to treat cases of male impotence. Elli Lilly and Icos are currently marketing Cialis in the UK and other EU countries.
How does Cialis (tadalafil) work?
Cialis acts in the same way as Viagra, by blocking an enzyme called phosphodiesterase-5, or PDE-5. This helps the smooth muscles in the penis relax and widen, which allows for more blood to enter. As a result, you gain erections faster and easier with Cialis.

How well does Cialis (tadalafil) work?
Cialis is approved in these markets for the treatment of mild to severe ED at both 10 and 20 mg doses. The labels in each of these markets indicate that the product should be taken prior to anticipated sexual activity and without regard to food. Just like Viagra, sexual stimulation is needed for Cialis to work. According to the European label, the efficacy of Cialis may persist up to 24 hours after the pill is taken. In Australia the label indicates efficacy up to 36 hours after dosing.

Clinical Data Overview

More than 4,000 men have participated in more than 60 studies that characterized the safety and efficacy profile of Cialis. In primary efficacy studies involving 1,112 men (804 Cialis, 308 placebo) with mild to severe ED, up to 81 percent of those treated with Cialis reported improved erections compared with 35 percent of those taking placebo(1).

The most commonly reported adverse events were headache, upset stomach, nasal congestion, backache, muscle ache, dizziness, and flushing. The adverse events reported with Cialis were transient and generally mild or moderate. As with other PDE5 inhibitors, the use of Cialis is contraindicated in patients who are taking nitrates. It should not be taken by patients with certain heart diseases for whom sexual activity itself is not advisable.

Remember that no medicine is for everyone. If you take any form of nitrates, often prescribed to control chest pains, do not take Cialis. This combination could cause an unsafe drop in blood pressure.

What's the normal Cialis (tadalafil) dose?
In Cialis clinical testing most men were administered one 10 mg Cialis or 20 mg Cialis tablet per day.

Are there any side effects with Cialis (tadalafil)?
The most common side effects reported with Cialis in the study were headache, myalgia (muscle pain), dyspepsia (upset stomach following meals) and back pain. The severities of these Cialis side effects were minimized with lower doses of Cialis.

How They Compare

Cialis
How long it works: Up to 24 hours

Recommended time to take before sex: 30 minutes to 12 hours

Most common side effects: Headache, dyspepsia/upset stomach, back pain

Levitra

How long it works: Up to 5 hours

Recommended time to take before sex: 25 to 60 minutes

Most common side effects: Headache, facial flushing

Viagra

How long it works: Up to 4.5-5 hours

Recommended time to take before sex: 60 minutes

Most common side effects: Headache, facial flushing, altered or blueish vision

Sources: J.P. Morgan, European Agency for the Evaluation of Medicinal Products

Aspects of ED that were significantly improved by Cialis® include:

overall erectile function

ability to achieve erections sufficient for vaginal penetration

ability to maintain erections for successful sexual intercourse

satisfaction with sexual intercourse

overall satisfaction

satisfaction with the hardness of erections

confidence in ability to achieve and maintain an erection

partners' satisfaction with sexual intercourse

TryCialis.com is an informational site about Cialis. Only a doctor knows what's right for you. Cialis is a trademark of LillyIcos.